Dracula
"Spit" Harbors Life-Saving Potential
While the image of bats makes most people
cringe, and the mostly harmless creatures all seem to have a reputation
for blood-sucking thanks to Dracula, the truth is, that these tiny creatures
may be the key to life for stroke victims. And that key is held by the
vampire bat.
As a rule, the vampire bat takes in up
to 50g of blood a day. That consumption is not like sitting down to lunch
at McDonald’s. The process is slow, and takes hours. How then, do they
manage to keep the blood flowing, when their victims’ systems (generally
cows or donkeys in South American countries like Brazil) are pumping out
clotting factors into the tiny wounds?
Protein in the bat’s saliva keeps the blood
liquid and mobile, until they are done the meal. When their fangs withdraw,
the wound seals. Researchers who delved into the structure of that protein,
came up with the drug desmoteplase, currently manufactured in Germany by
the Paion company, and under study in 16 American institutions.
The drawing card for the duplicated "bat
spit", is the expanded time frame for treating stroke victims. Currently
the only approved drug for immediate use, is IV t-PA, which must be administered
within three hours of the onset of symptoms. Desmoteplase, widens that
window of opportunity to nine hours, which could mean the difference between
life and death, or crippling and total recovery.
So promising is the drug, that the American
Heart Association named it to their top ten list of advances in cardiac/stroke
medicines for 2003.
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